SPRAVATO® (Esketamine) Therapy in Texas & Colorado
A Breakthrough Treatment for Treatment-Resistant Depression
At Klarisana, we are proud to offer SPRAVATO® (esketamine) therapy, an innovative treatment for adults struggling with treatment-resistant depression (TRD) and Major Depressive Disorder with Suicidal Ideation (MDSI). SPRAVATO® is an FDA-approved nasal spray that works rapidly to relieve depressive symptoms. This cutting-edge therapy provides new hope for individuals who have not responded to traditional treatments.
How SPRAVATO® (Esketamine) Works
Unlike conventional antidepressants, which can take weeks to show effects, SPRAVATO® works differently by targeting the NMDA receptors in the brain. This mechanism promotes neuroplasticity, helping to rapidly improve mood and reduce symptoms of depression.
Key Benefits of SPRAVATO® Therapy:
- FDA-Approved for Treatment-Resistant Depression – Specifically designed for adults who haven’t responded to traditional antidepressants.
- Fast-Acting Relief – Many patients experience improvement in depressive symptoms within hours or days.
- Supervised Medical Administration – SPRAVATO® is administered in our clinic under the guidance of experienced medical professionals.
- Comprehensive Mental Health Support – Integrated into Klarisana’s holistic mental health care approach.
What to Expect During SPRAVATO® Treatment
Our dedicated team will guide you through the SPRAVATO® treatment process, ensuring a safe and supportive environment:
- Initial Consultation – A thorough evaluation to determine if SPRAVATO® is the right option for you.
- In-Clinic Administration – The nasal spray is self-administered under the supervision of our trained medical staff.
- Close Monitoring – Patients remain in a comfortable setting for at least two hours after each session for observation.
- Ongoing Treatment Plan – Our team provides continuous support and monitoring to optimize your results.
Who is Eligible for SPRAVATO®?
SPRAVATO® is intended for adults with treatment-resistant depression (TRD) who:
- Have tried at least two different oral antidepressants without significant improvement.
- Are experiencing Major Depressive Disorder with Suicidal Ideation (MDSI).
SPRAVATO® Treatment in Texas & Colorado
At Klarisana, we are committed to providing advanced mental health treatments in a safe, professional, and compassionate setting. Our clinics in Texas and Colorado offer SPRAVATO® therapy as part of our mission to help individuals regain control of their mental well-being.
Start Your Healing Journey Today
If you or a loved one is struggling with treatment-resistant depression or Major Depressive Disorder with Suicidal Ideation (MDSI), SPRAVATO® may be the breakthrough you’ve been searching for. Contact us today to schedule a consultation!
Success Stories
Great experience and great company. I’m so glad that this treatment is available for anyone experiencing anxiety, depression or PTSD…these treatments helped me feel strong enough…
… ketamine is the only treatment that gives me true, real, and lasting relief.
I feel like an actual person again and like I can live my life.
FAQ
Why does Klarisana exist?
Klarisana is not just a clinic, it’s also the fruition of our belief that we can help people who are in a dark season of life realign themselves with the unique mission for which each of them was created. We believe that each person was created for a purpose and has an important mission to fulfill in this lifetime. Chronic pain, severe depression, post-traumatic stress disorder (PTSD), and other mental health conditions derail a person’s ability to carry out their mission. We offer ketamine therapy, which represents a totally different paradigm in treatment.
What does ketamine therapy feel like?
Ketamine elicits changes in the perception of sights, sounds, time, and space. The experience can be described as “psychedelic” but that term is clouded by various characterizations in popular culture which do not accurately describe the experience. Generally, patients do not see things that are not there but they may have dreamlike visions. Many patients use terms like feeling “more connected to the universe.” This gets back to our treatment principle that these alterations are what “show” patients a new way to look at their reality. It is what leads to our axiom that “if you could put the experience into words then talk therapy would have already helped.”
As far as the clinical environment, our rooms are decorated in order to convey sensations of relaxation, tranquility and peacefulness. Rooms have large screen TVs where patients can watch naturescape videos. Some patients choose to use an eye mask and turn off the TV.
Patients receive their IM treatments in privacy while under constant observation during the ketamine session. We use high resolution video monitoring to augment direct observation by our clinical staff. The provider performs an initial evaluation and physical exam and steps out of the room once the IM treatment has started. Most ketamine sessions last about one and a half hours.
Are there specific risks or side effects related to ketamine use that patients should be aware of?
While ketamine is generally safe when administered properly, it can have side
effects such as dissociation, increased blood pressure, or nausea. We educate
patients about potential effects and closely monitor them throughout treatment.
Additionally, if patients have a medical or behavioral health condition that may
impact treatment outcomes, we make contact with their external providers to better
understand if our treatment is the best option for them prior to proceeding.
What is the difference between Intramuscular Injection (IM) and Intravenous (IV)?
Ketamine can be administered by a variety of routes. The two that lead to the most predictable dosing and response are intravenous (IV) administration and intramuscular (IM) administration. The Klarisana model is based on intramuscular injections of ketamine. For the first several years of our company history we provided IV ketamine. In 2020 we did a reevaluation of our operations and switched to an IM model. There were several reasons for this.
First off, the goal of treatment with ketamine in our clinics is very different from how ketamine was used in emergency departments (ED) and operating rooms (OR) traditionally. We are using ketamine to facilitate a powerful transformational experience by leveraging a non-ordinary state of consciousness…commonly thought of as a “psychedelic experience.” The doses we use are much less than what would be used in an anesthesia context and the purpose is fundamentally different. In our setting, we refer to it broadly as Ketamine for Non-Anesthetic Indications (KNAI). This is totally different from using the medication as an anesthetic.
One of the first things we realized is that the process of starting an IV can be traumatic. Many of our patients have significant anxiety to start with. Even the best clinicians will miss IVs. Having one or two missed attempts at an IV can really put a patient in a bad mental space.
The other thing is the way in which the ketamine is delivered. With an IV, the pump starts delivering it at a set rate over an hour. The point of maximum intensity where the patient has a profound experience does not occur until well over half way through the session. When they finally have a powerful experience the session is almost over.
Our protocol is to give two IM injections spaced apart by 10-15 minutes. This allows our patients to achieve the desired effect in the first third of their session. They then have much longer to explore that space and have a more constructive experience. Additionally, they also have more time for the medication to wear off prior to being discharged from the clinic. This increases patient comfort and safety as they are in a much clearer mindset when they leave the clinic.
After the switch to an IM model we published a case series of 40 patients with major depressive disorder. The results are very much in line with (and actually better than) the published literature using an IV based model. In 2022 we performed close to 20,000 IM ketamine sessions with a great deal of success and an excellent safety record.
Is ketamine treatment at Klarisana covered by insurance?
Our commitment is to make ketamine therapy accessible and affordable to the largest number of patients possible and we are working hard to increase the number of Health Plans we are in network with. Visit our Insurance Page for updates on which new services are covered by our in-network insurance providers.
Does Klarisana provide primary mental health services?
Klarisana patients are welcome to continue to see our Licensed Mental Health providers for therapy outside of ketamine-assisted psychotherapy. However, Klarisana does not manage medications nor do we prescribe them for our patients. We are a healthcare organization that works very hard to perfect the art of administering ketamine for mental health conditions and chronic pain, as well as providing quality mental health care access.
Although in certain locations we do provide mental health services outside of ketamine therapy, we still work closely with psychiatrists and psychologists in our communities to partner with them to offer a valuable treatment option to their patients. Patients without a psychiatrist or psychologist can still access our mental health providers.
The environment in which ketamine is administered and the experience that a patient has is absolutely vital to increasing a patient’s chance of success. This is not the kind of therapy that lends itself to just being an “add-on” revenue stream for a clinic that has an “extra office.” We do it right and we do it effectively. We feel that the role of the psychiatrist in a patient’s care is vital but there is nothing to be gained from having them present during the actual session. Far from trying to replace or compete with local psychiatrists, we strive to be an effective resource that they can have at their disposal to treat their patients.
